產品詳情
簡單介紹：
Anti-AIRE抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-AIRE抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-AIRE
Cat. Number:
Anti-AIRE抗體KL-12453R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The autoimmune regulator gene, which is defective in the hereditary auto-immune disease APECED, encodes the transcriptional activator AIRE. AIRE is expressed in the medullary epithelial cells and monocyte-dendritic Anti-AIRE抗體cells of the thymus, with lower expression in the spleen, fetal liver and lymph nodes. In ***** tissue, AIRE expression in the thymus is confined to the medulla and the cortico-medullary junction, where it is modulated by thymocytes undergoing negative selection. At the cellular level, AIRE is located in microtubular structures of the cyto-skeleton and in discrete nuclear dots resembling ND10 nuclear bodies. AIRE is induced by developing early thymocytes and is associated with the correct establishment of a regular thymic environment. AIRE regulates thymic architecture via transcriptional control of downstream target genes. AIRE mutations in APECED patients may affect thymic T cell selection and the formation of self-tolerance.
Also known as:
Anti-AIRE抗體AIRE-1; AIRE; AIRE_HUMAN; AIRE1; APECED; APECED protein; APS1; APSI; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; Autoimmune regulator; Autoimmune regulator protein; PGA1.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Horse, .
●
Immunogen: KLH conjugated synthetic peptide derived from human PGA1/AIRE.
●
Predicted Molecular Weight: 58kDa.
Storage:
Shipped at 4℃, Anti-AIRE抗體Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Anti-AIRE抗體Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Anti-AIRE抗體Optimal working dilutions must be determined by the end user.
kl872Hu01 CD3d分子(CD3d)多克隆抗體 Polyclonal Antibody to Cluster Of Differentiation 3d (CD3d)
kl873Hu01 CD19分子(CD19)多克隆抗體 Polyclonal Antibody to Cluster Of Differentiation 19 (CD19)
kl873Mu01 CD19分子(CD19)多克隆抗體 Polyclonal Antibody to Cluster Of Differentiation 19 (CD19)
kl873Ra01 CD19分子(CD19)多克隆抗體 Polyclonal Antibody to Cluster Of Differentiation 19 (CD19)
kl874Hu01 凝血因子Ⅶ(F7)多克隆抗體 Polyclonal Antibody to Coagulation Factor VII (F7)
kl874Mu01 凝血因子Ⅶ(F7)多克隆抗體 Polyclonal Antibody to Coagulation Factor VII (F7)
kl874Ra01 凝血因子Ⅶ(F7)多克隆抗體 Polyclonal Antibody to Coagulation Factor VII (F7)
kl875Hu01 角蛋白13(KRT13)多克隆抗體 Polyclonal Antibody to Keratin 13 (KRT13)
kl876Hu01 高遷移率族核小體結合域蛋白1(HMGN1)多克隆抗體 Polyclonal Antibody to High Mobility Group Nucleosome Binding Domain Protein 1 (HMGN1)
kl877Hu01 叉頭框蛋白P3(FOXP3)多克隆抗體 Polyclonal Antibody to Forkhead Box Protein P3 (FOXP3)
kl877Mu01 叉頭框蛋白P3(FOXP3)多克隆抗體 Polyclonal Antibody to Forkhead Box Protein P3 (FOXP3)
kl878Hu01 凝血因子Ⅷ(F8)多克隆抗體 Polyclonal Antibody to Coagulation Factor VIII (F8)
kl878Mu01 凝血因子Ⅷ(F8)多克隆抗體 Polyclonal Antibody to Coagulation Factor VIII (F8)
kl879Hu01 載脂蛋白F(APOF)多克隆抗體 Polyclonal Antibody to Apolipoprotein F (APOF)
kl879Ra01 載脂蛋白F(APOF)多克隆抗體 Polyclonal Antibody to Apolipoprotein F (APOF)
